Defining, Identifying, and Evaluating Clinical Trials of Stuttering Treatments: A Tutorial for Clinicians Purpose To develop a method for clinicians to evaluate stuttering treatment efficacy research with very little burden of work. Method The clinical trial is the most fundamental, clinically interpretable, and useful output unit of stuttering treatment research. We define a clinical trial of a stuttering treatment and specify ... Tutorial
Tutorial  |   November 01, 2008
Defining, Identifying, and Evaluating Clinical Trials of Stuttering Treatments: A Tutorial for Clinicians
 
Author Affiliations & Notes
  • Mark Onslow
    Australian Stuttering Research Centre, The University of Sydney
  • Mark Jones
    Queensland Clinical Trials Centre, University of Queensland, Australia
  • Sue O’Brian
    Australian Stuttering Research Centre, The University of Sydney
  • Ross Menzies
    Australian Stuttering Research Centre, The University of Sydney
  • Ann Packman
    Australian Stuttering Research Centre, The University of Sydney
  • Contact author: Mark Onslow, Australian Stuttering Research Centre, The University of Sydney, Gate 2 East Street, Lidcombe, NSW, Australia. E-mail: m.onslow@usyd.edu.au.
Article Information
Speech, Voice & Prosodic Disorders / Fluency Disorders / Research Issues, Methods & Evidence-Based Practice / Tutorial
Tutorial   |   November 01, 2008
Defining, Identifying, and Evaluating Clinical Trials of Stuttering Treatments: A Tutorial for Clinicians
American Journal of Speech-Language Pathology, November 2008, Vol. 17, 401-415. doi:10.1044/1058-0360(2008/07-0047)
History: Received June 26, 2007 , Accepted February 25, 2008
 
American Journal of Speech-Language Pathology, November 2008, Vol. 17, 401-415. doi:10.1044/1058-0360(2008/07-0047)
History: Received June 26, 2007; Accepted February 25, 2008
Web of Science® Times Cited: 25

Purpose To develop a method for clinicians to evaluate stuttering treatment efficacy research with very little burden of work.

Method The clinical trial is the most fundamental, clinically interpretable, and useful output unit of stuttering treatment research. We define a clinical trial of a stuttering treatment and specify 3 levels of clinical trials evidence. We use this taxonomy to identify and evaluate clinical trials of stuttering treatment. Our taxonomy draws on 2 fundamental principles of clinical trials used to evaluate health care: randomization and effect size.

Results Published clinical trials of stuttering treatments were identified and allocated to 1 of 3 levels of evidence.

Conclusions We outline a 3-step, semi-automated, Internet-based method to identify the publication of a report of stuttering treatment efficacy. For a report identified as such, a 10-item checklist is applied to verify its status as a clinical trial and to allocate it to 1 of 3 levels of clinical trials evidence. The present taxonomy reduces the burden of work of a 136-item checklist in an existing taxonomy.

Acknowledgments
We acknowledge Martin Nevdahl’s useful editing of the manuscript. This project was supported by Program Grant 402763 from the National Health and Medical Research Council of Australia (NHMRC).
Order a Subscription
Pay Per View
Entire American Journal of Speech-Language Pathology content & archive
24-hour access
This Article
24-hour access